Josh Segarra’s role in Fox’s ‘Best Medicine’ isn’t just another acting gig—it’s a love letter to his childhood. The actor reveals how the show’s set is sprinkled with Easter eggs from his real life, including photos from his parents’ pharmacy, making the series a deeply personal project that resonates with his own family history.
The Show That Feels Like Home
Fox’s Best Medicine, an adaptation of the beloved British series Doc Martin, isn’t just another medical dramedy. For Josh Segarra, who plays the earnest Sheriff Mark Mylow, the show is a deeply personal journey. In an exclusive interview with People, Segarra revealed that the set of Best Medicine is adorned with Easter eggs from his childhood, including photos from his parents’ pharmacy. These touches transform the fictional town of Port Wenn into a space that feels like home.
Segarra’s parents are pharmacists, and his on-screen mother, played by Clea Lewis, runs the town’s pharmacy. The actor shared that the set designers incorporated personal mementos, such as photos his mother displayed in her real-life pharmacy. “It’s just cherries on top of a sundae,” Segarra told People. “And this one has a lot of cherries on top that mean a lot to me.”
A Character Built on Earnestness and Heartbreak
Sheriff Mark Mylow is a man defined by his sincerity. Segarra describes him as “unabashedly earnest,” a character who wears his heart on his sleeve even after a devastating breakup. When the show begins, Mark is nursing a broken heart after his fiancée, schoolteacher Louisa Gavin (Abigail Spencer), ends their engagement. His emotional vulnerability makes him relatable, a quality Segarra embraces wholeheartedly.
“He may not know everything, but he has no problem telling you that he doesn’t know everything,” Segarra explained. “It’s a very freeing character to play because he just loves really hard, and he wants to protect his town.” This earnestness is what drew Segarra to the role. He saw himself in Mark’s journey, particularly the way the character’s life changes when Dr. Martin Best (Josh Charles) arrives in Port Wenn. “Little did Dr. Martin know that Sheriff Mark needed him at this exact right time,” Segarra reflected.
Why ‘Best Medicine’ Stands Out in a Crowded TV Landscape
Best Medicine premieres at a time when audiences crave authenticity. The show’s blend of humor, heart, and small-town charm sets it apart from the typical medical drama. For Segarra, the project was a no-brainer. “If I read something and it makes me laugh out loud, I’m going to do it,” he said. “I knew Sheriff Mark. I feel like I could bring myself into the character.”
The series also boasts a stellar cast, including Annie Potts, Cree, and Stephen Spinella, alongside guest appearances by Martin Clunes, the original star of Doc Martin. This mix of talent ensures that Best Medicine delivers both emotional depth and comedic timing, making it a standout in Fox’s lineup.
A Family Affair: Why Segarra’s Parents Approve
One of the most touching aspects of Segarra’s involvement in Best Medicine is how it resonates with his family. As the son of two pharmacists, Segarra grew up in an environment similar to the one depicted on screen. His wife, Brace Rice, and their three young sons can watch the show together, making it a rare project that appeals to all generations.
“I feel fortunate to have a role in a show that my whole family can watch and enjoy,” Segarra shared. The personal Easter eggs scattered throughout the set—like the photos in the pharmacy—add an extra layer of meaning for him. “It’s those little things that make it special,” he said.
What’s Next for ‘Best Medicine’?
Best Medicine premieres on Sunday, January 4, on Fox, before settling into its regular timeslot on Tuesdays beginning January 6. Episodes will be available to stream on Hulu and Disney+ the following day, ensuring that fans won’t miss a moment of the small-town drama.
The show’s premise—a big-city doctor returning to a quaint town after a traumatic experience—is familiar, but its execution is anything but. With Segarra’s personal connection to the material and a cast that brings warmth and authenticity to every scene, Best Medicine is poised to become a fan favorite.
The Bigger Picture: Why This Story Matters
In an era where TV often prioritizes spectacle over substance, Best Medicine offers something rare: a story about healing, community, and the quiet moments that define us. Segarra’s decision to infuse the set with pieces of his own history isn’t just a creative choice—it’s a testament to the power of storytelling. By blending his real-life experiences with his on-screen role, he creates a character that feels authentic, relatable, and deeply human.
For fans of Doc Martin, this adaptation is a chance to revisit a beloved world with fresh eyes. For newcomers, it’s an invitation to fall in love with a town where everyone knows your name—and your secrets. And for Segarra, it’s a reminder that sometimes, the best medicine isn’t found in a prescription, but in the people and places that make us feel at home.
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