Allison Janney’s Unforgettable Costars: Unpacking Her Candid Revelations on Set Experiences

6 Min Read

Allison Janney, known for her incredible range and candid humor, has recently stirred the waters of Hollywood with two separate, intriguing revelations about former costars. One, sadly deceased, she would refuse to work with again, and another, a self-proclaimed germaphobe, insisted on an unusual pre-kiss ritual. These anecdotes offer a fascinating peek behind the curtain of her illustrious career, sparking widespread fan discussion.

In Hollywood, where public personas often reign supreme, Allison Janney stands out for her refreshing honesty. The acclaimed actress, a fan favorite across film and television, has recently offered two distinct, equally surprising insights into her past on-set experiences, each leaving audiences intrigued and admiring her ability to navigate complex professional relationships.

The Deceased Costar She’d ‘Never Work With Again’

During an October 2025 appearance on Andy Cohen’s “Watch What Happens Live!”, alongside her “The Diplomat” costar Keri Russell, Allison Janney, 65, responded to a question about former colleagues she would refuse to work with again. Both Janney and Russell initially agreed with the sentiment using “agree” signs, but it was Janney’s follow-up that caught everyone’s attention.

She clarified that the actor in question was no longer alive, stating, “Well, mine is no longer with us, so I really can’t — I really couldn’t work with them again, even if I wanted to.” Despite encouragement from Russell and Cohen to name names, Janney politely declined, citing her mother’s sage advice: “My mom would say ‘In the car, windows up, out of the driveway,’ ” a humorous but firm stance on criticizing others publicly.

This revelation immediately sparked conversations among fans about who the deceased costar could possibly be, a testament to Janney’s extensive and varied career. While she remained tight-lipped, her commitment to privacy, even posthumously, resonated with many who appreciate her discretion. The details of her “Watch What Happens Live!” appearance were widely reported by publications like People.

Dia Dipasupil/WireImage Allison Janney on Aug. 25, 2025
Allison Janney attending an event in August 2025, continuing her active presence in Hollywood.

The ‘Germaphobe’ Who Required Neosporin for Kissing Scenes

Years prior, in a January 2021 interview on “Jimmy Kimmel Live!”, Allison Janney, then 61, shared another unusual costar anecdote. She recalled a pre-COVID-19 experience with a “germaphobe” scene partner who had a peculiar request before a kissing scene. “He was such a germaphobe, he would put Neosporin on his lips and ask me to put it on mine, too, before he would kiss me,” Janney explained.

She admitted that the request “kind of unnerved” her, adding, “I didn’t know [what it would do] but I took it very personally, though. I thought, ‘what does he think I put in my mouth?'” Host Jimmy Kimmel jokingly asked if it was Howie Mandel, known for his fear of germs, but Janney confirmed it was not, once again choosing to keep the identity of her costar private.

This story highlights the unique and sometimes awkward demands that can arise in the intimate environment of a film set. Janney’s ability to recount such a personal and slightly uncomfortable experience with humor and grace is a testament to her character. These details were widely reported by various entertainment outlets at the time.

A Legacy of Candidness and Professionalism

Allison Janney’s willingness to share these experiences, while always maintaining a respectful boundary, offers fans a glimpse into the human side of moviemaking. Her mother’s “in the car, windows up, out of the driveway” advice has clearly guided her career, allowing her to speak her truth without resorting to public shaming.

Beyond these intriguing revelations, Janney has consistently made headlines for her work. Her recent roles include portraying the President of the United States in Netflix’s “The Diplomat” and appearing in films like “The Roses,” “Everything’s Going to Be Great,” and “Another Simple Favor.”

She has also been candid about other significant professional shifts, such as the departure of her longtime costar Anna Faris from the popular CBS sitcom “Mom.” Janney openly shared her feelings about Faris’s exit, calling it “a huge loss for the show” and expressing how much she would miss their onscreen dynamic, as reported by Entertainment Tonight. This consistent openness, balanced with her firm privacy boundaries, has only endeared her further to her dedicated fanbase.

Dia Dipasupil/Getty Allison Janney on Oct. 14, 2025
A recent portrait of Allison Janney from October 2025, showcasing her enduring presence in entertainment.

These behind-the-scenes stories, while tantalizingly vague on specific names, underscore the unpredictable nature of collaborative artistry and the professionalism required to navigate its challenges. Allison Janney’s ability to share these tales without compromising confidentiality only solidifies her reputation as a true class act in Hollywood.

Share This Article